TNFRSF10A
tumor necrosis factor receptor superfamily, member 10a
Synonyms:
APO2, CD261, DR4, TRAILR-1, TRAILR1
Species:
UniProtKB ID:
Gene ID:
- Human(8797) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
- cow(781763) tumor necrosis factor receptor superfamily, member 10a
- domestic guinea pig(101787877) tumor necrosis factor receptor superfamily, member 10a
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