TIMP1
TIMP metallopeptidase inhibitor 1
Synonyms:
CLGI, EPA, EPO, HCI, TIMP
Species:
Human TIMP1 (7076), Mouse Timp1 (21857), Rat Timp1 (116510), domestic cat TIMP1 (101095886), naked mole-rat Timp1 (101722238), dog TIMP1 (403816), cow TIMP1 (282092), domestic guinea pig Timp1 (101787552), sheep TIMP1 (443331), Horse TIMP1 (100034220)
UniProtKB ID:
Gene ID:
- Human(7076) Summary: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]
- Mouse(21857) tissue inhibitor of metalloproteinase 1
- Rat(116510) TIMP metallopeptidase inhibitor 1
- domestic cat(101095886) TIMP metallopeptidase inhibitor 1
- naked mole-rat(101722238) TIMP metallopeptidase inhibitor 1
- dog(403816) TIMP metallopeptidase inhibitor 1
- cow(282092) TIMP metallopeptidase inhibitor 1
- domestic guinea pig(101787552) TIMP metallopeptidase inhibitor 1
- sheep(443331) TIMP metallopeptidase inhibitor 1
- Horse(100034220) TIMP metallopeptidase inhibitor 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TIMP-1 Antibody, Chemicon®, from rabbit,
Species Reactivity
bovine, ferret, horse, rabbit, rat, sheep
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TIMP-1 Antibody, clone 7-6C1, clone 7-6C1, Chemicon®, from mouse,
Species Reactivity
bovine, human, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TIMP1 Antibody, clone 5O7P1, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot
Anti-TIMP1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit, sheep
Application
western blot
Anti-TIMP-1 (Ab-1) Mouse mAb (7-6C1), liquid, clone 7-6C1, Calbiochem®,
Species Reactivity
bovine, human, rat
Application
Proteins
Product Number
Description
Species
TIMP-1 human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human