SYN3
synapsin III
Synonyms:
Species:
Human SYN3 (8224), Mouse Syn3 (27204), Rat Syn3 (29130), naked mole-rat Syn3 (101715067), Domestic Rabbit SYN3 (100328740), domestic guinea pig Syn3 (100735324), Horse SYN3 (100146694), dog SYN3 (481290), domestic cat SYN3 (101090954), cow SYN3 (100138309) ...More
UniProtKB ID:
Gene ID:
- Human(8224) Summary: This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction. Alternative splicing of this gene results in multiple splice variants that encode different isoforms. [provided by RefSeq, Oct 2008]
- Mouse(27204) synapsin III
- Rat(29130) synapsin III
- naked mole-rat(101715067) synapsin III
- Domestic Rabbit(100328740) synapsin III
- domestic guinea pig(100735324) synapsin III
- Horse(100146694) synapsin III
- dog(481290) synapsin III
- domestic cat(101090954) synapsin III
- cow(100138309) synapsin III
- Thale Cress(825124) sister chromatid cohesion 1 protein 3
- chicken(100857420) synapsin III
- sheep(101118937) synapsin III
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