Skip to Content
Merck

SIRT5

sirtuin 5

Synonyms:
SIR2L5
Species:
UniProtKB ID:
Gene ID:
  • Human(23408) Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2010]
  • Mouse(68346) sirtuin 5
  • Rat(306840) sirtuin 5
  • Goat(100860989) sirtuin 5
  • cow(507347) sirtuin 5
  • naked mole-rat(101718891) sirtuin 5
  • dog(478726) sirtuin 5
  • domestic cat(101089862) sirtuin 5
  • chicken(420834) sirtuin 5
  • Zebrafish(436878) sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)
  • domestic guinea pig(100718110) sirtuin 5
  • sheep(101104099) sirtuin 5

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Sirt5 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
chimpanzee, human, rat, rhesus macaque
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SIRT5,
Species
human