SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
Synonyms:
PI12, neuroserpin
Species:
Human SERPINI1 (5274), Mouse Serpini1 (20713), Rat Serpini1 (116459), dog SERPINI1 (478684), naked mole-rat Serpini1 (101716288), domestic guinea pig Serpini1 (100733658), chicken SERPINI1 (425002), sheep SERPINI1 (101122566), Horse SERPINI1 (100057410), Domestic Rabbit SERPINI1 (100341797) ...More
UniProtKB ID:
Gene ID:
- Human(5274) Summary: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
- Mouse(20713) serine (or cysteine) peptidase inhibitor, clade I, member 1
- Rat(116459) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- dog(478684) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- naked mole-rat(101716288) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- domestic guinea pig(100733658) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- chicken(425002) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- sheep(101122566) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- Horse(100057410) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- Domestic Rabbit(100341797) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- Zebrafish(557627) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- domestic cat(101090383) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- cow(509976) serpin peptidase inhibitor, clade I (neuroserpin), member 1
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Proteins
Product Number
Description
Species
Neuroserpin human, recombinant, expressed in E. coli, ≥96% (SDS-PAGE), ≥96% (HPLC), suitable for cell culture,
Species
human