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Merck

SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

Synonyms:
CERIII, CIAT, EIEE13, MED, NaCh6, Nav1.6, PN4
Species:
Human SCN8A (6334), Mouse Scn8a (20273), Rat Scn8a (29710), chicken SCN8A (100857835), dog SCN8A (477604), Horse SCN8A (100052777), cow SCN8A (537277), naked mole-rat Scn8a (101711868), domestic guinea pig Scn8a (100734003), sheep SCN8A (101113744) ...More
UniProtKB ID:
Q9UQD0, B9VWG8, O95788, Q9NYX2, Q9UPB2
Gene ID:
  • Human(6334) Summary: This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(20273) sodium channel, voltage-gated, type VIII, alpha
  • Rat(29710) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(100857835) sodium channel, voltage gated, type VIII, alpha subunit
  • dog(477604) sodium channel, voltage gated, type VIII, alpha subunit
  • Horse(100052777) sodium channel, voltage gated, type VIII, alpha subunit
  • cow(537277) sodium channel, voltage gated, type VIII, alpha subunit
  • naked mole-rat(101711868) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic guinea pig(100734003) sodium channel, voltage gated, type VIII, alpha subunit
  • sheep(101113744) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic cat(101096578) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(426869) sodium channel, voltage gated, type VIII, alpha subunit

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Antibodies

Product Number
Description
Species Reactivity
Application
AB5580
Anti-SCN8A Sodium Channel Antibody, Chemicon®, from rabbit,
Species Reactivity
mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
HPA073590
Anti-SCN8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
HPA043937
Anti-SCN8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence

Small Molecule - Blocker

Product Number
Description
Species
PHR1161
Procaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
34076
Phenazopyridine hydrochloride, VETRANAL®, analytical standard,
Species
human
P3100000
Procaine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
PHR1067
Carbamazepine, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
PHR1034
Lidocaine, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

esiRNA

Product Number
Description
Species
EMU187341
MISSION® esiRNA, targeting mouse Scn8a,
Species
mouse