RNF216
ring finger protein 216
Synonyms:
CAHH, TRIAD3, U7I1, UBCE7IP1, ZIN
Species:
Human RNF216 (54476), Mouse Rnf216 (108086), Rat Rnf216 (304294), dog RNF216 (479760), naked mole-rat Rnf216 (101715043), domestic guinea pig Rnf216 (100733973), chicken RNF216 (416486), sheep RNF216 (101117640), cow RNF216 (534455), Horse RNF216 (100059097) ...More
UniProtKB ID:
Gene ID:
- Human(54476) Summary: This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. [provided by RefSeq, Jul 2008]
- Mouse(108086) ring finger protein 216
- Rat(304294) ring finger protein 216
- dog(479760) ring finger protein 216
- naked mole-rat(101715043) ring finger protein 216
- domestic guinea pig(100733973) ring finger protein 216
- chicken(416486) ring finger protein 216
- sheep(101117640) ring finger protein 216
- cow(534455) ring finger protein 216
- Horse(100059097) ring finger protein 216
- domestic cat(101099009) ring finger protein 216
- Domestic Rabbit(100341909) ring finger protein 216
- Zebrafish(559441) ring finger protein 216
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