RASA2
RAS p21 protein activator 2
Synonyms:
GAP1M
Species:
Human RASA2 (5922), Mouse Rasa2 (114713), Rat Rasa2 (25597), naked mole-rat Rasa2 (101725433), chicken RASA2 (424782), Zebrafish rasa2 (327449), dog RASA2 (485692), Horse RASA2 (100063323), domestic cat RASA2 (101098329), cow RASA2 (533491) ...More
UniProtKB ID:
Gene ID:
- Human(5922) Summary: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein; a compound suggested to function as a second messenger. [provided by RefSeq, Jul 2008]
- Mouse(114713) RAS p21 protein activator 2
- Rat(25597) RAS p21 protein activator 2
- naked mole-rat(101725433) RAS p21 protein activator 2
- chicken(424782) RAS p21 protein activator 2
- Zebrafish(327449) RAS p21 protein activator 2
- dog(485692) RAS p21 protein activator 2
- Horse(100063323) RAS p21 protein activator 2
- domestic cat(101098329) RAS p21 protein activator 2
- cow(533491) RAS p21 protein activator 2
- Domestic Rabbit(100357503) RAS p21 protein activator 2
- sheep(101108362) RAS p21 protein activator 2
- domestic guinea pig(100730767) RAS p21 protein activator 2
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