PSMD13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
Synonyms:
HSPC027, Rpn9, S11, p40.5
Species:
Human PSMD13 (5719), Mouse Psmd13 (23997), Rat Psmd13 (365388), domestic guinea pig Psmd13 (100714436), naked mole-rat Psmd13 (101698107), sheep PSMD13 (101104945), cow PSMD13 (513525), Horse PSMD13 (100050948), domestic cat PSMD13 (101101591), dog PSMD13 (475934) ...More
UniProtKB ID:
Gene ID:
- Human(5719) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(23997) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
- Rat(365388) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
- domestic guinea pig(100714436) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
- naked mole-rat(101698107) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
- sheep(101104945) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
- cow(513525) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
- Horse(100050948) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
- domestic cat(101101591) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
- dog(475934) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
- chicken(422990) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
- Zebrafish(393922) proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
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