POU6F2
POU class 6 homeobox 2
Synonyms:
RPF-1, WT5, WTSL
Species:
Human POU6F2 (11281), Mouse Pou6f2 (218030), Rat Pou6f2 (681092), chicken POU6F2 (420763), sheep POU6F2 (101120407), cow POU6F2 (517861), domestic cat POU6F2 (101099283), dog POU6F2 (483249), naked mole-rat Pou6f2 (101707418), domestic guinea pig Pou6f2 (100719507)
UniProtKB ID:
Gene ID:
- Human(11281) Summary: This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
- Mouse(218030) POU domain, class 6, transcription factor 2
- Rat(681092) POU domain, class 6, transcription factor 2
- chicken(420763) POU class 6 homeobox 2
- sheep(101120407) POU class 6 homeobox 2
- cow(517861) POU class 6 homeobox 2
- domestic cat(101099283) POU class 6 homeobox 2
- dog(483249) POU class 6 homeobox 2
- naked mole-rat(101707418) POU class 6 homeobox 2
- domestic guinea pig(100719507) POU class 6 homeobox 2
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