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Merck

POU5F1

POU class 5 homeobox 1

Synonyms:
OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4
Species:
UniProtKB ID:
Gene ID:
  • Human(5460) Summary: This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Mar 2010]
  • Mouse(18999) POU domain, class 5, transcription factor 1
  • Rat(294562) POU class 5 homeobox 1
  • sheep(100302349) POU class 5 homeobox 1
  • cow(282316) POU class 5 homeobox 1
  • domestic cat(100174788) POU class 5 homeobox 1
  • dog(481709) POU class 5 homeobox 1
  • Goat(100861237) POU class 5 homeobox 1
  • domestic guinea pig(100724951) POU class 5 homeobox 1
  • Domestic Rabbit(100101567) POU class 5 homeobox 1
  • naked mole-rat(101722299) POU class 5 homeobox 1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Human Oct-4 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
chimpanzee, goat, human
Application
immunocytochemistry
western blot
Monoclonal Anti-POU5F1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL7621, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-Oct-4 Antibody, clone 10H11.2, Alexa Fluor 488 conjugate, clone 10H11.2, from mouse, ALEXA FLUOR 488,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry
Anti-Oct-4 Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-Oct-4 Antibody, clone 9B7, clone 9B7, from mouse,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human POU5F1 (2),
Species
human
MISSION® esiRNA, targeting mouse Pou5f1,
Species
mouse
MISSION® esiRNA, targeting human POU5F1 (1),
Species
human