POT1
protection of telomeres 1
Synonyms:
HPOT1
Species:
Human POT1 (25913), Rat Pot1 (500054), chicken POT1 (404538), Zebrafish pot1 (566847), domestic guinea pig Pot1 (100725051), naked mole-rat Pot1 (101698900), sheep POT1 (101107695), cow POT1 (511292), Horse POT1 (100071610), domestic cat POT1 (101097225)
UniProtKB ID:
Gene ID:
- Human(25913) Summary: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
- Rat(500054) protection of telomeres 1
- chicken(404538) protection of telomeres 1 homolog (S. pombe)
- Zebrafish(566847) protection of telomeres 1 homolog
- domestic guinea pig(100725051) protection of telomeres 1
- naked mole-rat(101698900) protection of telomeres 1
- sheep(101107695) protection of telomeres 1 homolog (S. pombe)
- cow(511292) protection of telomeres 1
- Horse(100071610) protection of telomeres 1 homolog (S. pombe)
- domestic cat(101097225) protection of telomeres 1 homolog (S. pombe)
- dog(609119) protection of telomeres 1 homolog (S. pombe)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-POT1 Antibody, clone 43B7, ,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
western blot
esiRNA
Product Number
Description
Species