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Merck

PON2

paraoxonase 2

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(5445) Summary: This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(330260) paraoxonase 2
  • Rat(296851) paraoxonase 2
  • chicken(395830) paraoxonase 2
  • Zebrafish(335176) paraoxonase 2
  • naked mole-rat(101697694) paraoxonase 2
  • domestic guinea pig(100721821) paraoxonase 2
  • sheep(100145861) paraoxonase 2
  • Domestic Rabbit(100340152) paraoxonase 2
  • cow(281417) paraoxonase 2
  • domestic cat(101094492) paraoxonase 2
  • dog(403855) paraoxonase 2

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PON2 Antibody, clone 1B6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Pon2,
Species
mouse
MISSION® esiRNA, targeting human PON2,
Species
human