PKD2
polycystic kidney disease 2 (autosomal dominant)
Synonyms:
APKD2, PC2, PKD4, Pc-2, TRPP2
Species:
Human PKD2 (5311), Mouse Pkd2 (18764), Rat Pkd2 (498328), chicken PKD2 (422585), Zebrafish pkd2 (432387), dog PKD2 (487852), Domestic Rabbit PKD2 (100008872), sheep PKD2 (101103569), naked mole-rat Pkd2 (101726639), domestic cat PKD2 (101098948) ...More
UniProtKB ID:
Gene ID:
- Human(5311) Summary: This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011]
- Mouse(18764) polycystic kidney disease 2
- Rat(498328) polycystic kidney disease 2 (autosomal dominant)
- chicken(422585) polycystic kidney disease 2 (autosomal dominant)
- Zebrafish(432387) polycystic kidney disease 2
- dog(487852) polycystic kidney disease 2 (autosomal dominant)
- Domestic Rabbit(100008872) polycystic kidney disease 2 (autosomal dominant)
- sheep(101103569) polycystic kidney disease 2 (autosomal dominant)
- naked mole-rat(101726639) polycystic kidney disease 2 (autosomal dominant)
- domestic cat(101098948) polycystic kidney disease 2 (autosomal dominant)
- domestic guinea pig(100714947) polycystic kidney disease 2 (autosomal dominant)
- fruit fly(34651) Polycystic kidney disease gene-2
- cow(530393) polycystic kidney disease 2 (autosomal dominant)
Custom & Knockdown Gene Products
siRNA
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Custom Gene Products
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Polycystin-L Antibody, serum, Chemicon®,
Species Reactivity
mouse
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Polycystin-2 Antibody, serum, Chemicon®,
Species Reactivity
mouse
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Product Number
Description
Species
PKD2 Recombinant Human Protein, Active, 10 µg, Active, N-terminal His6 tagged, recombinant, full length, human PKD2, for use in Kinase Assays.,
Species