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Merck

PFKL

phosphofructokinase, liver

Synonyms:
PFK-B
Species:
UniProtKB ID:
Gene ID:
  • Human(5211) Summary: Phosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. Separate genes encode a muscle subunit (M) and a liver subunit (L). PFK from muscle is a homotetramer of M subunits, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits. The protein encoded by this gene represents the L subunit. Alternate splicing results in two transcript variants, one of which is a candidate for nonsense-mediated decay (NMD). [provided by RefSeq, Aug 2008]
  • Mouse(18641) phosphofructokinase, liver, B-type
  • Rat(25741) phosphofructokinase, liver
  • dog(487797) phosphofructokinase, liver
  • chicken(769850) phosphofructokinase, liver
  • domestic guinea pig(100720033) phosphofructokinase, liver
  • domestic cat(101090792) phosphofructokinase, liver
  • cow(508683) phosphofructokinase, liver
  • naked mole-rat(101724978) phosphofructokinase, liver

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Kits

Product Number
Description
Species
Phosphofructokinase (PFK) Activity Colorimetric Assay Kit, sufficient for 100 colorimetric tests,
Species
mouse, rat, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PFKL,
Species
human
MISSION® esiRNA, targeting mouse Pfkl,
Species
mouse