PEX3
peroxisomal biogenesis factor 3
Synonyms:
PBD10A, TRG18
Species:
Human PEX3 (8504), Mouse Pex3 (56535), Rat Pex3 (83519), domestic guinea pig Pex3 (100715215), chicken PEX3 (421669), naked mole-rat Pex3 (101724411), dog PEX3 (484015), domestic cat PEX3 (101091448), cow PEX3 (515730), Domestic Rabbit PEX3 (100353686) ...More
UniProtKB ID:
Gene ID:
- Human(8504) Summary: The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS). [provided by RefSeq, Oct 2008]
- Mouse(56535) peroxisomal biogenesis factor 3
- Rat(83519) peroxisomal biogenesis factor 3
- domestic guinea pig(100715215) peroxisomal biogenesis factor 3
- chicken(421669) peroxisomal biogenesis factor 3
- naked mole-rat(101724411) peroxisomal biogenesis factor 3
- dog(484015) peroxisomal biogenesis factor 3
- domestic cat(101091448) peroxisomal biogenesis factor 3
- cow(515730) peroxisomal biogenesis factor 3
- Domestic Rabbit(100353686) peroxisomal biogenesis factor 3
- Thale Cress(841285) peroxin 3
- sheep(101118110) peroxisomal biogenesis factor 3
- Zebrafish(393197) peroxisomal biogenesis factor 3
- fruit fly(39652) Peroxin 3
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