OSGIN1
oxidative stress induced growth inhibitor 1
Synonyms:
BDGI, OKL38
Species:
Human OSGIN1 (29948), Mouse Osgin1 (71839), Rat Osgin1 (171493), sheep OSGIN1 (101122544), dog OSGIN1 (489687), domestic cat OSGIN1 (101086865), Horse OSGIN1 (100070078), chicken OSGIN1 (415706), domestic guinea pig Osgin1 (100731240), naked mole-rat Osgin1 (101715060)
UniProtKB ID:
Gene ID:
- Human(29948) Summary: This gene encodes an oxidative stress response protein that regulates cell death. Expression of the gene is regulated by p53 and is induced by DNA damage. The protein regulates apoptosis by inducing cytochrome c release from mitochondria. It also appears to be a key regulator of both inflammatory and anti-inflammatory molecules. The loss of this protein correlates with uncontrolled cell growth and tumor formation. Naturally occurring read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase (MLYCD) gene, but the read-through transcripts are unlikely to produce a protein product. [provided by RefSeq, Aug 2011]
- Mouse(71839) oxidative stress induced growth inhibitor 1
- Rat(171493) oxidative stress induced growth inhibitor 1
- sheep(101122544) oxidative stress induced growth inhibitor 1
- dog(489687) oxidative stress induced growth inhibitor 1
- domestic cat(101086865) oxidative stress induced growth inhibitor 1
- Horse(100070078) oxidative stress induced growth inhibitor 1
- chicken(415706) oxidative stress induced growth inhibitor 1
- domestic guinea pig(100731240) oxidative stress induced growth inhibitor 1
- naked mole-rat(101715060) oxidative stress induced growth inhibitor 1
- cow(768073) oxidative stress induced growth inhibitor 1
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