OPA1
optic atrophy 1 (autosomal dominant)
Synonyms:
MGM1, NPG, NTG, largeG
Species:
Human OPA1 (4976), Mouse Opa1 (74143), Rat Opa1 (171116), cow OPA1 (524142), chicken OPA1 (424900), sheep OPA1 (101106813), dog OPA1 (477129), Zebrafish opa1 (492332), domestic cat OPA1 (101086671), Domestic Rabbit OPA1 (100344494) ...More
UniProtKB ID:
Gene ID:
- Human(4976) Summary: This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
- Mouse(74143) optic atrophy 1
- Rat(171116) optic atrophy 1
- cow(524142) optic atrophy 1 (autosomal dominant)
- chicken(424900) optic atrophy 1 (autosomal dominant)
- sheep(101106813) optic atrophy 1 (autosomal dominant)
- dog(477129) optic atrophy 1 (autosomal dominant)
- Zebrafish(492332) optic atrophy 1 (human)
- domestic cat(101086671) optic atrophy 1 (autosomal dominant)
- Domestic Rabbit(100344494) optic atrophy 1 (autosomal dominant)
- Horse(100059993) optic atrophy 1 (autosomal dominant)
- domestic guinea pig(100717402) optic atrophy 1 (autosomal dominant)
- naked mole-rat(101698766) optic atrophy 1 (autosomal dominant)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-OPA1 Antibody, clone 1F15 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-OPA1, clone 1OPA-1A8 Antibody, ascites fluid, clone 10PA-1A8, from mouse,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot