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Merck

NSL1

NSL1, MIS12 kinetochore complex component

Synonyms:
C1orf48, MIS14
Species:
UniProtKB ID:
Gene ID:
  • Human(25936) Summary: This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(381318) NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
  • Rat(498310) NSL1, MIS12 kinetochore complex component
  • Thale Cress(839735) MAC/Perforin domain-containing protein
  • chicken(421367) NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
  • Zebrafish(562522) NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
  • Horse(100050694) NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
  • domestic cat(101082714) NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
  • sheep(101115297) NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
  • cow(506867) NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
  • domestic guinea pig(100721544) NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
  • dog(480025) NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Mis12 Complex, from rabbit,
Species Reactivity
human
Application
immunocytochemistry
immunofluorescence

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human NSL1,
Species
human
MISSION® esiRNA, targeting mouse Nsl1,
Species
mouse