NDUFA1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
Synonyms:
CI-MWFE, MWFE, ZNF183
Species:
Human NDUFA1 (4694), Mouse Ndufa1 (54405), Rat Ndufa1 (363441), dog NDUFA1 (481033), domestic cat NDUFA1 (101085609), chicken NDUFA1 (772150), naked mole-rat Ndufa1 (101713738), Zebrafish ndufa1 (415243), cow NDUFA1 (327673), sheep NDUFA1 (100216464)
UniProtKB ID:
Gene ID:
- Human(4694) Summary: The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the 'hydrophobic protein' (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008]
- Mouse(54405) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
- Rat(363441) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
- dog(481033) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
- domestic cat(101085609) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
- chicken(772150) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
- naked mole-rat(101713738) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
- Zebrafish(415243) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
- cow(327673) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
- sheep(100216464) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
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