NAALAD2
N-acetylated alpha-linked acidic dipeptidase 2
Synonyms:
GCPIII, GPCIII, NAADALASE2, NAALADASE2
Species:
Human NAALAD2 (10003), Mouse Naalad2 (72560), Rat Naalad2 (300384), dog NAALAD2 (485139), naked mole-rat Naalad2 (101722660), cow NAALAD2 (536439), sheep NAALAD2 (101120451), domestic guinea pig Naalad2 (100726280), Horse NAALAD2 (100050187), Domestic Rabbit NAALAD2 (100339446) ...More
UniProtKB ID:
Gene ID:
- Human(10003) Summary: This gene is a member of the N-acetylated alpha-linked acidic dipeptidase (NAALADase) gene family. The representative member of this family is the gene encoding human prostate-specific membrane antigen (PSM), which is a marker of prostatic carcinomas and is the first to be shown to possess NAALADase activity. NAALADase cleaves N-acetyl-L-aspartate-L-glutamate (NAAG), which is a neuropeptide expressed both in the central nervous systems and in the periphery and is thought to function as a neurotransmitter. The product of this gene is a type II integral membrane protein. Transient transfection of this gene confers both NAALADase and dipetidyl peptidase IV activities to mammalian cells. This gene is highly expressed in ovary and testis as well as within discrete brain areas. [provided by RefSeq, Jul 2008]
- Mouse(72560) N-acetylated alpha-linked acidic dipeptidase 2
- Rat(300384) N-acetylated alpha-linked acidic dipeptidase 2
- dog(485139) N-acetylated alpha-linked acidic dipeptidase 2
- naked mole-rat(101722660) N-acetylated alpha-linked acidic dipeptidase 2
- cow(536439) N-acetylated alpha-linked acidic dipeptidase 2
- sheep(101120451) N-acetylated alpha-linked acidic dipeptidase 2
- domestic guinea pig(100726280) N-acetylated alpha-linked acidic dipeptidase 2
- Horse(100050187) N-acetylated alpha-linked acidic dipeptidase 2
- Domestic Rabbit(100339446) N-acetylated alpha-linked acidic dipeptidase 2
- chicken(419010) N-acetylated alpha-linked acidic dipeptidase 2
- domestic cat(101089389) N-acetylated alpha-linked acidic dipeptidase 2
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