MUTYH
mutY homolog
Synonyms:
CYP2C, MYH
Species:
Human MUTYH (4595), Mouse Mutyh (70603), Rat Mutyh (170841), domestic guinea pig Mutyh (100723877), naked mole-rat Mutyh (101706875), sheep MUTYH (101119344), dog MUTYH (482515), domestic cat MUTYH (101089880), Horse MUTYH (100052596), cow MUTYH (513051) ...More
UniProtKB ID:
Gene ID:
- Human(4595) Summary: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(70603) mutY homolog (E. coli)
- Rat(170841) mutY homolog (E. coli)
- domestic guinea pig(100723877) mutY homolog (E. coli)
- naked mole-rat(101706875) mutY homolog (E. coli)
- sheep(101119344) mutY homolog (E. coli)
- dog(482515) mutY homolog (E. coli)
- domestic cat(101089880) mutY homolog (E. coli)
- Horse(100052596) mutY homolog (E. coli)
- cow(513051) mutY homolog (E. coli)
- Zebrafish(558403) mutY homolog (E. coli)
- chicken(424594) mutY homolog (E. coli)
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