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Merck

MGST1

microsomal glutathione S-transferase 1

Synonyms:
GST12, MGST, MGST-I
Species:
UniProtKB ID:
Gene ID:
  • Human(4257) Summary: The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene. [provided by RefSeq, May 2012]
  • Mouse(56615) microsomal glutathione S-transferase 1
  • Rat(171341) microsomal glutathione S-transferase 1
  • naked mole-rat(101713569) microsomal glutathione S-transferase 1
  • domestic cat(101099565) microsomal glutathione S-transferase 1
  • sheep(101103462) microsomal glutathione S-transferase 1
  • domestic guinea pig(100736210) microsomal glutathione S-transferase 1
  • chicken(418178) microsomal glutathione S-transferase 1
  • dog(477683) microsomal glutathione S-transferase 1
  • cow(493719) microsomal glutathione S-transferase 1
  • Zebrafish(449784) microsomal glutathione S-transferase 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MGST1 Antibody, clone 6A0S5, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
Microsomes from Liver, Pooled, from mouse(CD-1), female,
Species
mouse
Microsomes from Liver, Pooled, from mouse(CD-1), male,
Species
mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MGST1,
Species
human