MAPK7
mitogen-activated protein kinase 7
Synonyms:
BMK1, ERK4, ERK5, PRKM7
Species:
Human MAPK7 (5598), Mouse Mapk7 (23939), Rat Mapk7 (114509), Zebrafish mapk7 (541323), domestic cat MAPK7 (101097357), cow MAPK7 (537703), dog MAPK7 (489532), Domestic Rabbit MAPK7 (100338535), sheep MAPK7 (101110073), naked mole-rat Mapk7 (101726391)
UniProtKB ID:
Gene ID:
- Human(5598) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(23939) mitogen-activated protein kinase 7
- Rat(114509) mitogen-activated protein kinase 7
- Zebrafish(541323) mitogen-activated protein kinase 7
- domestic cat(101097357) mitogen-activated protein kinase 7
- cow(537703) mitogen-activated protein kinase 7
- dog(489532) mitogen-activated protein kinase 7
- Domestic Rabbit(100338535) mitogen-activated protein kinase 7
- sheep(101110073) mitogen-activated protein kinase 7
- naked mole-rat(101726391) mitogen-activated protein kinase 7
- domestic guinea pig(100728396) mitogen-activated protein kinase 7
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ERK5 Antibody, clone 5C1P5, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Anti-ERK5 Antibody, clone 2H15 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, feline, human, monkey, mouse, porcine
Application
ELISA
affinity binding assay
immunofluorescence
immunohistochemistry
western blot
affinity binding assay
immunofluorescence
immunohistochemistry
western blot
Anti-phospho-BMK1/Erk5 (Thr218/Tyr220) Antibody, Upstate®, from rabbit,
Species Reactivity
bovine, human, mouse, rat
Application
inhibition assay
western blot
western blot