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Merck

MAF

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog

Synonyms:
CCA4, c-MAF
Species:
UniProtKB ID:
Gene ID:
  • Human(4094) Summary: The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
  • Mouse(17132) avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
  • Rat(54267) v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
  • Zebrafish(114467) v-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog
  • chicken(693248) v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
  • cow(782481) v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
  • domestic guinea pig(100725532) v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
  • naked mole-rat(101698937) v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-c-Maf Antibody, clone 1V7W3, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunoprecipitation (IP)
western blot