LZTS1
leucine zipper, putative tumor suppressor 1
Synonyms:
F37, FEZ1
Species:
Human LZTS1 (11178), Mouse Lzts1 (211134), Rat Lzts1 (266711), domestic guinea pig Lzts1 (100726802), naked mole-rat Lzts1 (101704547), Zebrafish lzts1 (569281), chicken LZTS1 (431331), dog LZTS1 (486136), domestic cat LZTS1 (101092354), Horse LZTS1 (100053630) ...More
UniProtKB ID:
Gene ID:
- Human(11178) Summary: This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer. [provided by RefSeq, Nov 2009]
- Mouse(211134) leucine zipper, putative tumor suppressor 1
- Rat(266711) leucine zipper, putative tumor suppressor 1
- domestic guinea pig(100726802) leucine zipper, putative tumor suppressor 1
- naked mole-rat(101704547) leucine zipper, putative tumor suppressor 1
- Zebrafish(569281) leucine zipper, putative tumor suppressor 1
- chicken(431331) leucine zipper, putative tumor suppressor 1
- dog(486136) leucine zipper, putative tumor suppressor 1
- domestic cat(101092354) leucine zipper, putative tumor suppressor 1
- Horse(100053630) leucine zipper, putative tumor suppressor 1
- cow(539634) leucine zipper, putative tumor suppressor 1
- sheep(101120987) leucine zipper, putative tumor suppressor 1
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