LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
BGL, CDC4L, CVID8, LAB300, LBA
Human LRBA (987), Mouse Lrba (80877), Rat Lrba (361975), Zebrafish lrba (100317557), chicken LRBA (422476), dog LRBA (475463), domestic cat LRBA (101093432), domestic guinea pig Lrba (100721090), cow LRBA (524279), sheep LRBA (101106365) ...More
- Human(987) Summary: The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
- Mouse(80877) LPS-responsive beige-like anchor
- Rat(361975) LPS-responsive vesicle trafficking, beach and anchor containing
- Zebrafish(100317557) LPS-responsive vesicle trafficking, beach and anchor containing
- chicken(422476) LPS-responsive vesicle trafficking, beach and anchor containing
- dog(475463) LPS-responsive vesicle trafficking, beach and anchor containing
- domestic cat(101093432) LPS-responsive vesicle trafficking, beach and anchor containing
- domestic guinea pig(100721090) LPS-responsive vesicle trafficking, beach and anchor containing
- cow(524279) LPS-responsive vesicle trafficking, beach and anchor containing
- sheep(101106365) LPS-responsive vesicle trafficking, beach and anchor containing
- naked mole-rat(101711663) LPS-responsive vesicle trafficking, beach and anchor containing
- Horse(100062459) LPS-responsive vesicle trafficking, beach and anchor containing
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