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Merck

LIN28B

lin-28 homolog B (C. elegans)

Synonyms:
CSDD2
Species:
Human LIN28B (389421), Mouse Lin28b (380669), Rat Lin28b (689054), chicken LIN28B (421786), sheep LIN28B (100861578), cow LIN28B (540646), domestic cat LIN28B (101090940), dog LIN28B (481943), domestic guinea pig Lin28b (100734141)
UniProtKB ID:
Q6ZN17, A1L165, B2RPN6, Q5TCM4
Gene ID:
  • Human(389421) Summary: The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
  • Mouse(380669) lin-28 homolog B (C. elegans)
  • Rat(689054) lin-28 homolog B (C. elegans)
  • chicken(421786) lin-28 homolog B (C. elegans)
  • sheep(100861578) lin-28 homolog B (C. elegans)
  • cow(540646) lin-28 homolog B (C. elegans)
  • domestic cat(101090940) lin-28 homolog B (C. elegans)
  • dog(481943) lin-28 homolog B (C. elegans)
  • domestic guinea pig(100734141) lin-28 homolog B (C. elegans)

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB5701695
Anti-LIN28B antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
MABE885
Anti-Lin-28B, clone 15G3 Antibody, clone 15G3, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
MABE884
Anti-Lin-28B, clone 17A2 Antibody, clone 17A2, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
ZRB2199
Anti-LIN28B Antibody, clone 1H17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
ABE1068
Anti-Lin-28B Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, human, porcine
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EMU204151
MISSION® esiRNA, targeting mouse Lin28b,
Species
mouse
EHU050781
MISSION® esiRNA, targeting human LIN28B,
Species
human