KLK7
kallikrein-related peptidase 7
Synonyms:
PRSS6, SCCE, hK7
Species:
Human KLK7 (5650), Mouse Klk7 (23993), Rat Klk7 (292852), cow KLK7 (506380), dog KLK7 (611780), sheep KLK7 (101115562), chicken KLK7 (769009), domestic guinea pig Klk7 (100716524), domestic cat KLK7 (101088894), naked mole-rat Klk7 (101705516)
UniProtKB ID:
Gene ID:
- Human(5650) Summary: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
- Mouse(23993) kallikrein related-peptidase 7 (chymotryptic, stratum corneum)
- Rat(292852) kallikrein-related peptidase 7
- cow(506380) kallikrein-related peptidase 7
- dog(611780) kallikrein-related peptidase 7
- sheep(101115562) kallikrein-related peptidase 7
- chicken(769009) kallikrein-related peptidase 7
- domestic guinea pig(100716524) kallikrein-related peptidase 7
- domestic cat(101088894) kallikrein-related peptidase 7
- naked mole-rat(101705516) kallikrein-related peptidase 7
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Kallikrein 7 (KLK7) Antibody, clone 83-1, clone 83-1, from mouse,
Species Reactivity
human
Application
ELISA
western blot
western blot