Skip to Content
Merck

KLK3

kallikrein-related peptidase 3

Synonyms:
APS, KLK2A1, PSA, hK3
Species:
Human KLK3 (354)
UniProtKB ID:
P07288, C9JXH3, G3V0H4, G3XAE3, Q15096, Q16272, Q86TG8, Q8IXI4
Gene ID:
  • Human(354) Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
AMAB91569
Monoclonal Anti-KLK3 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL9422, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
AMAB91567
Monoclonal Anti-KLK3 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL9414, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
ZRB1972
Anti-PSA Antibody, clone 1E10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
MABX5523
Anti-PSA (10mg) KC, from mouse,
Species Reactivity
human
Application
ELISA
immunodiffusion
SAB4702007
Monoclonal Anti-PSA Biotin produced in mouse, ,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
SRP6058
Kallikrein-3 human, recombinant, expressed in human cells, ≥95% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
EHU156951
MISSION® esiRNA, targeting human KLK3,
Species
human