KDM4C
lysine (K)-specific demethylase 4C
Synonyms:
GASC1, JHDM3C, JMJD2C, TDRD14C, bA146B14.1
Species:
Human KDM4C (23081), Mouse Kdm4c (76804), Rat Kdm4c (298144), Horse KDM4C (100060699), naked mole-rat Kdm4c (101698040), dog KDM4C (474704), Domestic Rabbit KDM4C (100343440), cow KDM4C (535671), chicken KDM4C (427231), sheep KDM4C (101117992) ...More
UniProtKB ID:
Gene ID:
- Human(23081) Summary: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
- Mouse(76804) lysine (K)-specific demethylase 4C
- Rat(298144) lysine (K)-specific demethylase 4C
- Horse(100060699) lysine (K)-specific demethylase 4C
- naked mole-rat(101698040) lysine (K)-specific demethylase 4C
- dog(474704) lysine (K)-specific demethylase 4C
- Domestic Rabbit(100343440) lysine (K)-specific demethylase 4C
- cow(535671) lysine (K)-specific demethylase 4C
- chicken(427231) lysine (K)-specific demethylase 4C
- sheep(101117992) lysine (K)-specific demethylase 4C
- domestic guinea pig(100719980) lysine (K)-specific demethylase 4C
- domestic cat(101100423) lysine (K)-specific demethylase 4C
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