IL7
interleukin 7
Synonyms:
IL-7
Species:
Human IL7 (3574), Mouse Il7 (16196), Rat Il7 (25647), chicken IL7 (420193), dog IL7 (751768), domestic cat IL7 (101084597), cow IL7 (280827), sheep IL7 (443341), domestic guinea pig Il7 (100725811), naked mole-rat Il7 (101713773)
UniProtKB ID:
Gene ID:
- Human(3574) Summary: The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.[provided by RefSeq, Dec 2010]
- Mouse(16196) interleukin 7
- Rat(25647) interleukin 7
- chicken(420193) interleukin 7
- dog(751768) interleukin 7
- domestic cat(101084597) interleukin 7
- cow(280827) interleukin 7
- sheep(443341) interleukin 7
- domestic guinea pig(100725811) interleukin 7
- naked mole-rat(101713773) interleukin 7
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1, clone 7B1.1, from mouse,
Species Reactivity
human
Application
flow cytometry
western blot
western blot
esiRNA
Product Number
Description
Species