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Merck

HNF4A

hepatocyte nuclear factor 4, alpha

Synonyms:
HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14
Species:
Human HNF4A (3172), Mouse Hnf4a (15378), Rat Hnf4a (25735), cow HNF4A (509200), sheep HNF4A (100534656), dog HNF4A (485884), Zebrafish hnf4a (322358), chicken HNF4A (419198), domestic guinea pig Hnf4a (100713275), naked mole-rat Hnf4a (101710133) ...More
UniProtKB ID:
P41235, A5JW41, B2RPP8, O00659, O00723, Q14540, Q5QPB8, Q6B4V5
Gene ID:
  • Human(3172) Summary: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012]
  • Mouse(15378) hepatic nuclear factor 4, alpha
  • Rat(25735) hepatocyte nuclear factor 4, alpha
  • cow(509200) hepatocyte nuclear factor 4, alpha
  • sheep(100534656) hepatocyte nuclear factor 4, alpha
  • dog(485884) hepatocyte nuclear factor 4, alpha
  • Zebrafish(322358) hepatocyte nuclear factor 4, alpha
  • chicken(419198) hepatocyte nuclear factor 4, alpha
  • domestic guinea pig(100713275) hepatocyte nuclear factor 4, alpha
  • naked mole-rat(101710133) hepatocyte nuclear factor 4, alpha
  • domestic cat(101092841) hepatocyte nuclear factor 4, alpha
  • Horse(100056007) hepatocyte nuclear factor 4, alpha

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Small Molecule - Activator

Product Number
Description
Species
Y0000687
Alverine citrate salt, European Pharmacopoeia (EP) Reference Standard,
Species
human
A0424
Alverine citrate salt, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
ZRB1457
Anti-HNF-4alpha Antibody, clone 4C19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EMU023811
MISSION® esiRNA, targeting mouse Hnf4a,
Species
mouse
EHU066741
MISSION® esiRNA, targeting human HNF4A,
Species
human