HDAC1
histone deacetylase 1
Synonyms:
GON-10, HD1, RPD3, RPD3L1
Species:
Human HDAC1 (3065), Mouse Hdac1 (433759), Rat Hdac1 (297893), chicken HDAC1 (373961), cow HDAC1 (404126), sheep HDAC1 (100820752), Zebrafish hdac1 (192302), domestic cat HDAC1 (101099228), naked mole-rat Hdac1 (101715102), domestic guinea pig Hdac1 (100728529)
UniProtKB ID:
Gene ID:
- Human(3065) Summary: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
- Mouse(433759) histone deacetylase 1
- Rat(297893) histone deacetylase 1
- chicken(373961) histone deacetylase 1
- cow(404126) histone deacetylase 1
- sheep(100820752) histone deacetylase 1
- Zebrafish(192302) histone deacetylase 1
- domestic cat(101099228) histone deacetylase 1
- naked mole-rat(101715102) histone deacetylase 1
- domestic guinea pig(100728529) histone deacetylase 1
- dog(487309) histone deacetylase 1
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Activity Assay
Product Number
Description
Species
Histone Deacetylase Assay Kit, Fluorometric, sufficient for 100 assays (96 well plates),
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti- HDAC1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-HDAC1 Antibody, clone 2E10, clone 2E10, Upstate®, from mouse,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot
western blot
Anti-HDAC1 Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
activity assay
immunocytochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
HDAC 1 from Plasmodium falciparum, recombinant, expressed in baculovirus infected insect cells, ≥40% (SDS-PAGE),
Species
esiRNA
Product Number
Description
Species