GPNMB
glycoprotein (transmembrane) nmb
Synonyms:
HGFIN, NMB
Species:
Human GPNMB (10457), Mouse Gpnmb (93695), Rat Gpnmb (113955), Zebrafish gpnmb (563348), naked mole-rat Gpnmb (101726702), dog GPNMB (482355), domestic guinea pig Gpnmb (100734622), sheep GPNMB (101109959), domestic cat GPNMB (101090001), chicken GPNMB (428431) ...More
UniProtKB ID:
Gene ID:
- Human(10457) Summary: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(93695) glycoprotein (transmembrane) nmb
- Rat(113955) glycoprotein (transmembrane) nmb
- Zebrafish(563348) glycoprotein (transmembrane) nmb
- naked mole-rat(101726702) glycoprotein (transmembrane) nmb
- dog(482355) glycoprotein (transmembrane) nmb
- domestic guinea pig(100734622) glycoprotein (transmembrane) nmb
- sheep(101109959) glycoprotein (transmembrane) nmb
- domestic cat(101090001) glycoprotein (transmembrane) nmb
- chicken(428431) glycoprotein (transmembrane) nmb
- cow(509600) glycoprotein (transmembrane) nmb
- Horse(100067870) glycoprotein (transmembrane) nmb
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