FLT1
fms-related tyrosine kinase 1
Synonyms:
FLT, FLT-1, VEGFR-1, VEGFR1
Species:
Human FLT1 (2321), Mouse Flt1 (14254), Rat Flt1 (54251), domestic guinea pig Flt1 (100732326), Zebrafish flt1 (544667), dog FLT1 (403727), domestic cat FLT1 (101088292), sheep FLT1 (443088), chicken FLT1 (374100), Horse FLT1 (100061940) ...More
UniProtKB ID:
Gene ID:
- Human(2321) Summary: This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
- Mouse(14254) FMS-like tyrosine kinase 1
- Rat(54251) FMS-related tyrosine kinase 1
- domestic guinea pig(100732326) fms-related tyrosine kinase 1
- Zebrafish(544667) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- dog(403727) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- domestic cat(101088292) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- sheep(443088) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- chicken(374100) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- Horse(100061940) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- cow(503620) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- Domestic Rabbit(100343352) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- Horse(100033957) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- naked mole-rat(101711333) fms-related tyrosine kinase 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-VEGFR1 Antibody, clone 7F1A3, Rabbit Monoclonal, ,
Species Reactivity
mouse, rat
Application
western blot
Anti-VEGF Receptor-1 Antibody, Chemicon®, from mouse,
Species Reactivity
human, mouse
Application
ELISA
western blot
western blot
Anti-phospho-Flt-1 (Tyr1213) Antibody, Upstate®, from rabbit,
Species Reactivity
bovine, goat, human, mouse, rat, sheep
Application
western blot
Small Molecule - Inhibitor
esiRNA
Product Number
Description
Species