FCAR
Fc fragment of IgA, receptor for
Synonyms:
CD89
Species:
Human FCAR (2204), Rat Fcar (365183), Horse FCAR (100050205), cow FCAR (503555), domestic guinea pig Fcar (100716057)
UniProtKB ID:
Gene ID:
- Human(2204) Summary: This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- Rat(365183) Fc fragment of IgA, receptor for
- Horse(100050205) Fc fragment of IgA, receptor for
- cow(503555) Fc fragment of IgA, receptor for
- domestic guinea pig(100716057) Fc fragment of IgA, receptor for
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