FBXL7
F-box and leucine-rich repeat protein 7
Synonyms:
FBL6, FBL7
Species:
Human FBXL7 (23194), Mouse Fbxl7 (448987), Rat Fbxl7 (361907), domestic guinea pig Fbxl7 (100720048), cow FBXL7 (518806), Horse FBXL7 (100070113), domestic cat FBXL7 (101089921), chicken FBXL7 (428492), dog FBXL7 (489262), sheep FBXL7 (101102932)
UniProtKB ID:
Gene ID:
- Human(23194) Summary: This gene encodes a member of the F-box protein family which is characterized by a 42-48 amino acid motif, the F-box, which binds to the S-phase kinase-associated protein 1 (Skp1) protein. The F-box proteins constitute one of the four subunits of E3 ubiquitin protein ligases called SCFs (SKP1-Cul1-F-box), which play a role in phosphorylation-dependent ubiquitination of proteins. The F-box proteins are divided into 3 subfamilies based on the other domain in the protein: F-box proteins that also have a WD-40 domain (Fbws subfamily), F-box proteins that also have leucine-rich repeats (Fbls subfamily) and F-box proteins that contain other motifs or lack known protein-interaction domains (Fbxs subfamily). The protein encoded by this gene belongs to the Fbls subfamily. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
- Mouse(448987) F-box and leucine-rich repeat protein 7
- Rat(361907) F-box and leucine-rich repeat protein 7
- domestic guinea pig(100720048) F-box and leucine-rich repeat protein 7
- cow(518806) F-box and leucine-rich repeat protein 7
- Horse(100070113) F-box and leucine-rich repeat protein 7
- domestic cat(101089921) F-box and leucine-rich repeat protein 7
- chicken(428492) F-box and leucine-rich repeat protein 7
- dog(489262) F-box and leucine-rich repeat protein 7
- sheep(101102932) F-box and leucine-rich repeat protein 7
- naked mole-rat(101700886) F-box and leucine-rich repeat protein 7
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