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Merck

EPOR

erythropoietin receptor

Synonyms:
EPO-R
Species:
UniProtKB ID:
Gene ID:
  • Human(2057) Summary: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(13857) erythropoietin receptor
  • Rat(24336) erythropoietin receptor
  • dog(484943) erythropoietin receptor
  • domestic cat(101081364) erythropoietin receptor
  • naked mole-rat(101710668) erythropoietin receptor
  • cow(281144) erythropoietin receptor
  • domestic guinea pig(100721190) erythropoietin receptor
  • Zebrafish(751109) erythropoietin receptor
  • sheep(443227) erythropoietin receptor

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-EPO-R Antibody, clone VP-2E8, clone VP-2E8, from mouse,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry

immunofluorescence

immunoprecipitation (IP)
Anti-EPO-R Antibody, clone BCO-3H2, clone BCO-3H2, from rat,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-EPOR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Epor,
Species
mouse