ELAC2
elaC ribonuclease Z 2
Synonyms:
ELC2, HPC2
Species:
Human ELAC2 (60528), Mouse Elac2 (68626), Rat Elac2 (282826), dog ELAC2 (489511), domestic cat ELAC2 (101087182), Zebrafish elac2 (492652), chicken ELAC2 (417313), domestic guinea pig Elac2 (100732820), naked mole-rat Elac2 (101723360), Domestic Rabbit ELAC2 (100342150) ...More
UniProtKB ID:
Gene ID:
- Human(60528) Summary: The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
- Mouse(68626) elaC homolog 2 (E. coli)
- Rat(282826) elaC ribonuclease Z 2
- dog(489511) elaC homolog 2 (E. coli)
- domestic cat(101087182) elaC homolog 2 (E. coli)
- Zebrafish(492652) elaC homolog 2 (E. coli)
- chicken(417313) elaC homolog 2 (E. coli)
- domestic guinea pig(100732820) elaC ribonuclease Z 2
- naked mole-rat(101723360) elaC ribonuclease Z 2
- Domestic Rabbit(100342150) elaC homolog 2 (E. coli)
- sheep(101104921) elaC homolog 2 (E. coli)
- cow(509256) elaC homolog 2 (E. coli)
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