DEGS1
delta(4)-desaturase, sphingolipid 1
Synonyms:
DEGS, DEGS-1, DES1, Des-1, FADS7, MLD
Species:
Human DEGS1 (8560), Mouse Degs1 (13244), Rat Degs1 (58970), Zebrafish degs1 (327075), chicken DEGS1 (421327), naked mole-rat Degs1 (101722992), sheep DEGS1 (100192315), cow DEGS1 (507290), domestic cat DEGS1 (101083993), dog DEGS1 (490395)
UniProtKB ID:
Gene ID:
- Human(8560) Summary: This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010]
- Mouse(13244) degenerative spermatocyte homolog 1 (Drosophila)
- Rat(58970) delta(4)-desaturase, sphingolipid 1
- Zebrafish(327075) degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)
- chicken(421327) degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)
- naked mole-rat(101722992) delta(4)-desaturase, sphingolipid 1
- sheep(100192315) delta(4)-desaturase, sphingolipid 1
- cow(507290) degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)
- domestic cat(101083993) delta(4)-desaturase, sphingolipid 1
- dog(490395) delta(4)-desaturase, sphingolipid 1
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