CUL4B
cullin 4B
Synonyms:
MRXHF2, MRXS15, MRXSC, SFM2
Species:
Human CUL4B (8450), Mouse Cul4b (72584), Rat Cul4b (302502), Horse CUL4B (100033938), domestic guinea pig Cul4b (100714185), sheep CUL4B (101113913), Domestic Rabbit CUL4B (100351102), naked mole-rat Cul4b (101711205), cow CUL4B (539668), Zebrafish cul4b (560313) ...More
UniProtKB ID:
Gene ID:
- Human(8450) Summary: This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(72584) cullin 4B
- Rat(302502) cullin 4B
- Horse(100033938) cullin 4B
- domestic guinea pig(100714185) cullin 4B
- sheep(101113913) cullin 4B
- Domestic Rabbit(100351102) cullin 4B
- naked mole-rat(101711205) cullin 4B
- cow(539668) cullin 4B
- Zebrafish(560313) cullin 4B
- dog(492102) cullin 4B
- chicken(422364) cullin 4B
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