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Merck

CTNNB1

catenin (cadherin-associated protein), beta 1, 88kDa

Synonyms:
CTNNB, MRD19, armadillo
Species:
Human CTNNB1 (1499), Mouse Ctnnb1 (12387), Rat Ctnnb1 (84353), Zebrafish ctnnb1 (30265), Horse CTNNB1 (100055241), chicken CTNNB1 (395964), domestic guinea pig Ctnnb1 (100732604), cow CTNNB1 (539003), domestic cat CTNNB1 (101097342), sheep CTNNB1 (100294600) ...More
UniProtKB ID:
P35222, A8K1L7, Q8NEW9, Q8NI94, Q9H391
Gene ID:
  • Human(1499) Summary: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009]
  • Mouse(12387) catenin (cadherin associated protein), beta 1
  • Rat(84353) catenin (cadherin associated protein), beta 1
  • Zebrafish(30265) catenin (cadherin-associated protein), beta 1
  • Horse(100055241) catenin (cadherin-associated protein), beta 1, 88kDa
  • chicken(395964) catenin (cadherin-associated protein), beta 1, 88kDa
  • domestic guinea pig(100732604) catenin (cadherin-associated protein), beta 1, 88kDa
  • cow(539003) catenin (cadherin-associated protein), beta 1, 88kDa
  • domestic cat(101097342) catenin (cadherin-associated protein), beta 1, 88kDa
  • sheep(100294600) catenin (cadherin-associated protein), beta 1, 88kDa
  • dog(477032) catenin (cadherin-associated protein), beta 1, 88kDa
  • Domestic Rabbit(100125985) catenin (cadherin-associated protein), beta 1, 88kDa
  • naked mole-rat(101720578) catenin (cadherin-associated protein), beta 1, 88kDa

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB6012223
Anti-phospho-beta Catenin (Thr41/Ser45) Antibody, clone 23GB3875, Rabbit Monoclonal, clone 23GB3875, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human, rat
Application
flow cytometry
immunofluorescence
western blot
C2363
Monoclonal Anti-phospho-β-Catenin (pSer33) antibody produced in mouse, clone BC-76, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
microarray
western blot
SAB5701324
Anti- β-Catenin antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
C8616
Monoclonal Anti-phospho-β-Catenin (pThr41) antibody produced in mouse, clone BCT-41, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunocytochemistry
immunoprecipitation (IP)
microarray
western blot
05-613
Anti-β-Catenin Antibody, clone 2H4A7, clone 2H4A7, Upstate®, from mouse,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot

esiRNA

Product Number
Description
Species
EHU139421
MISSION® esiRNA, targeting human CTNNB1,
Species
human
EMU047621
MISSION® esiRNA, targeting mouse Ctnnb1,
Species
mouse