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Merck

CNTNAP1

contactin associated protein 1

Synonyms:
CASPR, CNTNAP, NRXN4, P190
Species:
UniProtKB ID:
Gene ID:
  • Human(8506) Summary: The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. [provided by RefSeq, Jan 2009]
  • Mouse(53321) contactin associated protein-like 1
  • Rat(84008) contactin associated protein 1
  • domestic cat(101099341) contactin associated protein 1
  • domestic guinea pig(100719034) contactin associated protein 1
  • naked mole-rat(101714103) contactin associated protein 1
  • dog(490960) contactin associated protein 1
  • chicken(428309) contactin associated protein 1
  • Zebrafish(386706) contactin associated protein 1
  • cow(540997) contactin associated protein 1
  • sheep(101111565) contactin associated protein 1
  • Horse(100052467) contactin associated protein 1

Custom & Knockdown Gene Products

  • siRNA

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Caspr1 Antibody, clone 8O5H6, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-Caspr Antibody, clone K65/35, clone K65/35, from mouse,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Cntnap1,
Species
mouse
MISSION® esiRNA, targeting human CNTNAP1,
Species
human