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CNTF

ciliary neurotrophic factor

Synonyms:
HCNTF
Species:
UniProtKB ID:
Gene ID:
  • Human(1270) Summary: The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010]
  • Mouse(12803) ciliary neurotrophic factor
  • Rat(25707) ciliary neurotrophic factor
  • domestic cat(101097592) ciliary neurotrophic factor
  • chicken(396488) ciliary neurotrophic factor
  • Domestic Rabbit(100009117) ciliary neurotrophic factor
  • domestic guinea pig(100724905) ciliary neurotrophic factor
  • naked mole-rat(101713822) ciliary neurotrophic factor
  • dog(483464) ciliary neurotrophic factor
  • cow(100848228) ciliary neurotrophic factor

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Ciliary Neurotrophic Factor Antibody, clone 4-68, clone 4-68, Chemicon®, from mouse,
Species Reactivity
human, monkey, mouse, rat
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
CNTF, recombinant, ,
Species
rat
Ciliary Neurotrophic Factor human, CNTF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CNTF,
Species
human
MISSION® esiRNA, targeting human ZFP91, ZFP91-CNTF,
Species
human