CHUK
conserved helix-loop-helix ubiquitous kinase
Synonyms:
IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
Species:
Human CHUK (1147), Mouse Chuk (12675), Rat Chuk (309361), Zebrafish chuk (393287), naked mole-rat Chuk (101719306), domestic guinea pig Chuk (100726357), sheep CHUK (101111143), cow CHUK (281073), Horse CHUK (100070393), domestic cat CHUK (101095617) ...More
UniProtKB ID:
Gene ID:
- Human(1147) Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
- Mouse(12675) conserved helix-loop-helix ubiquitous kinase
- Rat(309361) conserved helix-loop-helix ubiquitous kinase
- Zebrafish(393287) conserved helix-loop-helix ubiquitous kinase
- naked mole-rat(101719306) conserved helix-loop-helix ubiquitous kinase
- domestic guinea pig(100726357) conserved helix-loop-helix ubiquitous kinase
- sheep(101111143) conserved helix-loop-helix ubiquitous kinase
- cow(281073) conserved helix-loop-helix ubiquitous kinase
- Horse(100070393) conserved helix-loop-helix ubiquitous kinase
- domestic cat(101095617) conserved helix-loop-helix ubiquitous kinase
- dog(477796) conserved helix-loop-helix ubiquitous kinase
- chicken(423669) conserved helix-loop-helix ubiquitous kinase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-IKKa (p45) Antibody, clone 881H3, clone 881H3, from mouse,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-p-IKKα/β-Ser176/180 Antibody, clone 2G2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, feline, human, monkey, mouse, porcine, rat
Application
affinity binding assay
immunohistochemistry
inhibition assay
western blot
immunohistochemistry
inhibition assay
western blot
Anti-IKKα Mouse mAb (14A231), liquid, clone 14A231, Calbiochem®,
Species Reactivity
human, monkey, mouse
Application
Anti-IKKα Antibody, clone 2M10E3, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
western blot
Anti-IKKα Antibody, clone 14A231, clone 14A231, Upstate®, from mouse,
Species Reactivity
human, monkey, mouse
Application
western blot
Proteins
Product Number
Description
Species
IKK α , active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
IKKα Protein, active, 10 µg, Active, recombinant full-length human IKKα, containing an N-terminal GST-tag, for use in Kinase Assays.,
Species
human
esiRNA
Small Molecule - Substrate
Product Number
Description
Species