CCL22
chemokine (C-C motif) ligand 22
Synonyms:
ABCD-1, DC/B-CK, MDC, SCYA22, STCP-1
Species:
Human CCL22 (6367), Mouse Ccl22 (20299), Rat Ccl22 (117551), dog CCL22 (100686212), naked mole-rat Ccl22 (101699782), domestic guinea pig Ccl22 (100716085), domestic cat CCL22 (101091326), cow CCL22 (616996), sheep CCL22 (101123141)
UniProtKB ID:
Gene ID:
- Human(6367) Summary: This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq, Jul 2008]
- Mouse(20299) chemokine (C-C motif) ligand 22
- Rat(117551) chemokine (C-C motif) ligand 22
- dog(100686212) chemokine (C-C motif) ligand 22
- naked mole-rat(101699782) chemokine (C-C motif) ligand 22
- domestic guinea pig(100716085) chemokine (C-C motif) ligand 22
- domestic cat(101091326) chemokine (C-C motif) ligand 22
- cow(616996) chemokine (C-C motif) ligand 22
- sheep(101123141) chemokine (C-C motif) ligand 22
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