CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
Synonyms:
CAMKA
Species:
Human CAMK2A (815), Mouse Camk2a (12322), Rat Camk2a (25400), Zebrafish camk2a (550436), Domestic Rabbit CAMK2A (100341507), dog CAMK2A (612941), domestic cat CAMK2A (101084342), cow CAMK2A (530719), naked mole-rat Camk2a (101722229), domestic guinea pig Camk2a (100727059) ...More
UniProtKB ID:
Gene ID:
- Human(815) Summary: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]
- Mouse(12322) calcium/calmodulin-dependent protein kinase II alpha
- Rat(25400) calcium/calmodulin-dependent protein kinase II alpha
- Zebrafish(550436) calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
- Domestic Rabbit(100341507) calcium/calmodulin-dependent protein kinase II alpha
- dog(612941) calcium/calmodulin-dependent protein kinase II alpha
- domestic cat(101084342) calcium/calmodulin-dependent protein kinase II alpha
- cow(530719) calcium/calmodulin-dependent protein kinase II alpha
- naked mole-rat(101722229) calcium/calmodulin-dependent protein kinase II alpha
- domestic guinea pig(100727059) calcium/calmodulin-dependent protein kinase II alpha
- Horse(100071654) calcium/calmodulin-dependent protein kinase II alpha
- chicken(374175) calcium/calmodulin-dependent protein kinase II alpha
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Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CaM Kinase II Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, chicken, guinea pig, hamster, human, mouse, rabbit, rat
Application
western blot
Anti-phospho-CaM Kinase II Antibody, α subunit, (Thr286), clone 22B1, clone 22B1, Upstate®, from mouse,
Species Reactivity
rat
Application
western blot
Monoclonal Anti-CAMK2A antibody produced in mouse, clone 2C12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-CaM Kinase II Antibody, α subunit, clone 6G9, clone 6G9, Upstate®, from mouse,
Species Reactivity
bovine, rat
Application
immunohistochemistry
western blot
western blot
Anti CaMKII Antibody, clone 23GB4370, Rabbit Monoclonal, clone 23GB4370, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human, rat
Application
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
CAMK2α, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
esiRNA
Small Molecule - Substrate
Product Number
Description
Species
Autocamtide 2-related inhibitory peptide, ≥97% (HPLC), lyophilized powder,
Species
mouse, rat, human