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Merck

CA4

carbonic anhydrase IV

Synonyms:
CAIV, Car4, RP17
Species:
UniProtKB ID:
Gene ID:
  • Human(762) Summary: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport. [provided by RefSeq, Jul 2008]
  • chicken(417647) carbonic anhydrase IV
  • dog(480591) carbonic anhydrase IV
  • domestic cat(101088531) carbonic anhydrase IV
  • cow(280741) carbonic anhydrase IV
  • sheep(101109718) carbonic anhydrase IV
  • Domestic Rabbit(100009226) carbonic anhydrase IV
  • domestic guinea pig(100731463) carbonic anhydrase IV
  • naked mole-rat(101700918) carbonic anhydrase IV

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Small Molecule - Activator

Product Number
Description
Species
D-Phenylalanine, ≥98% (HPLC),
Species
human
L-Phenylalanine, BioUltra, ≥99.0% (NT),
Species
human
L-Phenylalanine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%,
Species
human
L-Phenylalanine, reagent grade, ≥98%,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
Chlorothiazide, thiazide diuretic,
Species
human
Acetazolamide, European Pharmacopoeia (EP) Reference Standard,
Species
human
Acetazolamide for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Acetazolamide, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Dichlorphenamide, United States Pharmacopeia (USP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CA4,
Species
human