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Merck

BIRC3

baculoviral IAP repeat containing 3

Synonyms:
AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2
Species:
Human BIRC3 (330), Mouse Birc3 (11796), Rat Birc3 (78971), dog BIRC3 (489433), domestic cat BIRC3 (101083444), sheep BIRC3 (101120189), domestic guinea pig Birc3 (100713574), naked mole-rat Birc3 (101719143), Horse BIRC3 (100068894), cow BIRC3 (514386)
UniProtKB ID:
Q13489, Q16628, Q9HC27, Q9UP46
Gene ID:
  • Human(330) Summary: This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011]
  • Mouse(11796) baculoviral IAP repeat-containing 3
  • Rat(78971) baculoviral IAP repeat-containing 3
  • dog(489433) baculoviral IAP repeat containing 3
  • domestic cat(101083444) baculoviral IAP repeat containing 3
  • sheep(101120189) baculoviral IAP repeat containing 3
  • domestic guinea pig(100713574) baculoviral IAP repeat containing 3
  • naked mole-rat(101719143) baculoviral IAP repeat containing 3
  • Horse(100068894) baculoviral IAP repeat containing 3
  • cow(514386) baculoviral IAP repeat containing 3

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Antibodies

Product Number
Description
Species Reactivity
Application
MABC582
Anti-hIAP-1/BIRC3 Antibody, clone 11D12.1, clone 11D12.1, from mouse,
Species Reactivity
human
Application
western blot
ZRB2248
Anti-cIAP2/BIRC3 Antibody, clone 1N23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EHU067851
MISSION® esiRNA, targeting human BIRC3,
Species
human
EMU004361
MISSION® esiRNA, targeting mouse Birc3,
Species
mouse